منابع مشابه
Highlight: Changing the Canon—Revisiting a Classic Experiment to Alter the Genetic Code
It doesn’t take much for an organism to accept something radically new into its life. That is the conclusion of a recent inquiry into the mutability of life’s fundamental genetic code by Ting-Fung Chan, a computational biologist at the Chinese University of Hong Kong and his colleagues. “There are not actually that many genes involved in the change,” says Chan. For an organism to switch from us...
متن کاملExpanding the genetic code.
Although chemists can synthesize virtually any small organic molecule, our ability to rationally manipulate the structures of proteins is quite limited, despite their involvement in virtually every life process. For most proteins, modifications are largely restricted to substitutions among the common 20 amino acids. Herein we describe recent advances that make it possible to add new building bl...
متن کاملReprogramming the genetic code.
When Maria Leptin called to say that I had been awarded the 2010 EMBO Gold Medal, I was delighted and surprised. The roll call of past winners is impressive, and I had been at the Laboratory of Molecular Biology (LMB) when Jan Löwe had received the award in 2007 for his elegant work on the bacterial cytoskeleton (Michie and Löwe, 2006). I also knew that several other LMB scientists, including B...
متن کاملThe genetic code.
After the double-helical structure of DNA was revealed in 1953, researchers had before them the chance to unlock an utterly compelling puzzle, one for the ages and fundamental to the processes of life: What code linked DNA sequences to each of the 20 amino acids that comprised proteins? Every biology textbook now lists which three RNA bases correspond to which amino acid, but in 1961, that was ...
متن کاملThe Genetic Code
In this paper I will review the genetic code. An overview of its functions and inner workings will be given. Also the current theories on the origin and emergence of the canonical genetic code from early codes will be explored.
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2019
ISSN: 1759-6653
DOI: 10.1093/gbe/evz211